A new depsipeptide antibiotic, variapeptin.
نویسندگان
چکیده
A culture similar to Streptomyces variabilis was found to produce a novel cyclic hexadepsipeptide antibiotic named variapeptin. Variapeptin is structurally related to azinothricin, A83586C, and citropeptin. The antibiotic was active against Gram-positive bacteria and showed cytotoxic activity against mammalian cells.
منابع مشابه
Structural studies on new depsipeptide antibiotics, variapeptin and citropeptin.
Variapeptin and citropeptin were found as novel hexadepsipeptide antibiotics produced by Streptomyces variabilis and Streptomyces flavidovirens, respectively. Their structures were elucidated by NMR spectral analysis including a variety of 2D techniques. Variapeptin and citropeptin are structurally realted to azinothricin and A83586C, respectively.
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ورودعنوان ژورنال:
- Agricultural and biological chemistry
دوره 54 3 شماره
صفحات -
تاریخ انتشار 1990